Obesity hampers effects of anti-TNF agents
نویسندگان
چکیده
منابع مشابه
Common Adverse Effects of Anti-TNF Agents on Gestation
Autoimmune disease has affected up to 50 million Americans, according to the American Autoimmune Related Diseases Association (AARDA) and 75 percent of those affected are women. These inflammatory diseases have variable activity and a lot of women will have to undergo major therapies during and after pregnancy. Many of the women suffering from these disease will improve during gestation. Howeve...
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We have witnessed unprecedented advances in the past quarter of the century in our understanding of the pathophysiology of RA. Fortunately, for the majority of people presenting with this condition today, the outlook is much better than it would have been for those a generation ago. Many contemporary trainees in rheumatology might listen with incredulity when their senior colleagues describe th...
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In the past decade, tumour necrosis factor (TNF) antagonists have been found to be remarkably effective for the treatment of immune-mediated inflammatory disorders such as rheumatoid arthritis and Crohn’s disease. These agents also dramatically lessen inflammation and improve the quality of life in patients with psoriasis and psoriatic arthritis. The TNF-blocking agents have been relatively saf...
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OBJECTIVES Recent reports suggest efficacy of anti-tumour necrosis factor-alpha (TNF-α) therapy in Behçet's disease. However, the switching of anti-TNF-α agents for treatment failure remains unexplored. Our aims were to describe the efficacy and safety of a second anti-TNF-α agent in Behçet's disease patients after failure of a first agent. METHODS In this retrospective case series, 34 Behçet...
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ژورنال
عنوان ژورنال: Nature Reviews Rheumatology
سال: 2018
ISSN: 1759-4790,1759-4804
DOI: 10.1038/s41584-018-0018-4